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Ovulation Suppression Prevention of Implantation Barrier Methods
OVULATION SUPPRESSION The contraceptive pill works by suppressing or preventing ovulation. It contains a combination of synthetic estrogen and progesterone. The estrogen suppress FSH and LH secretion. (See This Page for more detail. The FSH and LH levels will decrease and there levels will be to low to stimulate the development of follicles in the ovary. If the follicles do not grow and enlarge, than ovulation can not occur and pregnancy is prevented. Another way of putting it is that the body ( via the pituitary gland) is tricked into believing that the ovaries are secreting to much hormones and the FSH and LH levels drop very low. This effect last only about thirty hours. That is way it is important to take the pill daily and at more or less the same time every day. The moment a pill is skipped or taken to late the FSH and LH levels can increase and a follicle might begin to develop. The inject able contraceptive ( an injection given every two or three months) also suppresses ovulation. The injection does not contain estrogen . It only contains synthetic progesterone like hormones in high doses. The inject able contraception also changes the mucus at the entrance of the cervix. The mucus becomes sticky and thick and the sperms can not penetrate the thick mucus. It also effects the endometrium . The endometrium stays thin and proliferation ( thickening ) of the endometrium is absent. The thin endometrium will prevent implantation in case ovulation should occur. The contraceptive pill also effects proliferation ( thickening) of the endometrium but to a lesser extent. A graphic illustration of the effects on the endometrium will follow later on this page. The side effects and complications will also be discussed later.
A foreign body in the uterine cavity will prevent implantation. This is the major mechanism through which
the so called "loop" or intra uterine device prevents pregnancies. It is a small plastic device that is
inserted into the uterus . It is left in the cavity for long periods ( up to five years). The modern devices
are T - shaped and a copper wire is wind around the lower element of the T. The copper wire constantly releases
copper ions . The ions effect the endometrium and make it unfavorable for implantation to occur.
A new type of intra uterine contraceptive device is now available. It continuously releases minute
amounts of progesterone in the uterine cavity. It has thus a progesterone effect locally on the endometrium
without or with very little systemic effect ( effects on other part of the body).
The progesterone only contraceptive pill ( only known as the mini pill)suppresses the
proliferation of the endometrium. It interferes with the preparation of the endometrium and prevents
implantation. It also makes the mucus at the entrance of the womb thick and sticky. The
thick mucus makes it difficult for the sperms to enter the womb.
A female condom is also available ( the edge of the condom sticks to the vulva{the organ around the vaginal opening} and sheath is inserted into the vagina. The contraceptive (progesterone) injection and the progesterone only pills have an effect on the cervical mucus making it more difficult for sperms to enter the womb. They thus have an effect on ovulation, implantation and a barrier effect.
The contraceptive pill refers to the combination pill that contains both female hormones namely estrogen and progesterone. It contains synthetic altered biochemical substances with estrogenic and progestogenic effects , but these synthetic hormones are much more potent than the normal hormones formed in the body.
The next illustration shows the effect of the pill on the endometrium.
(compare it with
THIS PAGE.
THE PILL usually consist of 21 active tablets ( containing estrogen and progesterone) and 7 placebo tablets (or "sugar tablets") containing no medical substances at all. While the placebo tablets are taken, there is is no endometrial stimulation and the inner layer of the endometrium is discarded .Menstruation begins.This amount of bleeding while you are on contraceptive tablets is usually less. This is due to the thinner endometrium. As soon as you start taking the active tablets again , the endometrium grows back and the bleeding stops.Compare it with the normal menstrual cycle HERE .
The next drawing shows the discarded endometrium with bleeding
We will now discuss possible side effects and complications due to oral contraception.
Irregular menstruations, spotting breakthrough bleedings.
When you are on "THE PILL" menstruation should occur every 28 days and it will normally start
when are taking the placebo ("sugar tablets") Bleeding that occurs at any other time is refer to
as breakthrough bleeding. It it a little it is referred to as spotting.
Skipping a tablet, having gastro enteritis ( vomiting and diaree)or certain medicines (certain antibiotics)
can also cause breakthrough bleeding. Not enough hormones are absorbed to keep the endometrium intact. The endometrium
is shed and a bleeding occurs at the wrong time.The antibiotics bind with the active ingredients of the pill forming
substances that are not absorb into the body. Always check with your doctor before taking medicines while on the
pill!
The pill hormones sometimes causes the lining to become so thin that the blood vessels are exposed and bleeding occur
at the wrong time.
These
bleedings tend to be temporary and are very common during the first few months . It is if your body has to get
use to "The pill". Depending on how heavy the bleeding and disturbing the bleeding is , it it possible to white a few months ( usually three)
and in most cases the abnormal bleeding will disappear. The same type of breakthrough bleeding also occur when changing
from one type of tablet to another type. If breakthrough bleedings persists ( longer than three months) or if it causing concern
please consult a doctor. There are few ways to manage the bleeding , but in the hands of a properly trained person.
Any breakthrough bleeding that start later( after the "pill" has been taken for a while without problems) should
be medically investigated.
This drawing illustrates breakthrough bleedings.
 
Sometimes "the pill" causes the endometrium to become very thin, so thin that
there is nothing to shed and the menstruations stop. If this occurs pregnancy should be excluded. The changes
of a pregnancy are however very slight. There is usually another reason why the menstruation stopped. Usually
due to the thin endometrium.
The pill is not fool proof and there is small change to conceive. The risk is about 1 in a thousand users per year. If a
thousand women use "the pill" for one year, one of them might conceive.
Some people might get mood swings, other might feel nausea while taking
the pill. People with a history of liver diseases should consult a doctor before
going on oral contraceptives. The same with persons who had blood clots previously.
Some people are concerned about a possible weight gain but many reseachers doubt if "the
pill" has major effect on body weight.
There was also some concern about a slight increased risk for developing breast cancer in the past,
but never proofed. "The pill " is in use for many years and no increased breast cancer risk was discovered
until now.
Smokers should not take the pill after age 35 due to an increase risk of blood clots and strokes.
However, "the pill " is with us for many years , millions of women took and are still taking it.
For the majority of them it was and is a save and reliable method of contraception. It is
by far the most popular method of contraception.
The Progesterone Only Pill.
In parts also known as the mini pill. (an outdated name)
It only contains one active hormone , progesterone. It has progesterone like effects on the
womb and endometrium. It is less effective than the combination pill to suppress ovulation.
It makes the cervical mucus at the entrance of the womb more sticky and less likely to allow sperms
to pass. It has the same effect on the endometrium as the combination pill . The lining will be thin
and more vascular. This can cause menstrual abnormalities in some women.
The thin lining will interfere with implantation.
The Progesterone Injection
The inject able contraceptives contains only progesterone in an inject able form , There are different
trademark available, an they are injected at two to three months intervals.
The absorption occurs very slowly (from the injection site) and that is way the injections have
a prolonged effect.
The endometrium becomes thin and vascular. Menstruation is usually suppressed (especially if the
3 monthly preparation are used). This means that menstruations are completely stopped while on the injections.
This will not cause any health risks. Menstruation is not a cleaning process , but only a sign that
inner part of the endometrium ( the mucus membrane that lines the inside of the womb) is discarded.
A fear of pregnancy is a concern in some women.
Due to its effect on the endometrium breakthrough bleedings and spottings can occur.
(a very thin vascular endometrium)
The progesterone injections are also used in the treatment of endometriosis ( due to their effect on the endometrium).
The intra uterine devices,
They usually increase the amount of bleeding. Vaginal infections are more common and
the risk of Salpingitis ( infections of the fallopian tubes) are also increased.
The manufactures of the progesterone releasing loop ( intra uterine device) claims but with
research evidence that it less likely to cause complications than the copper containing
device.
The effectiveness of the different methods
We will use the so called HUNDRED WOMEN YEAR method to compare the different methods. This is a only a rough
guide and some people with give slightly different figures.
If a hundred sexually active women are observed for one year:
1. If they do not use any form of contraception ,about 90 of them will become pregnant
2 If the use condoms there will be about 10 - 15 pregnancies.
3 If they use the copper containing intra uterine devices there will be about 10 pregnancies during
the first year it use , and about 6 pregnancies in later years.
(the longer the loop is used , the more effective it becomes.
4 If they use the progesterone only contraceptive about 6 pregnancies will occur.
5 If they use the combination pill, the contraceptive injection and the progesterone containing
intra uterine device , less than one pregnancy will occur per 100 women per year.
There are also other much less reliable methods not discussed on this page.
The include the save period, the with drawl method and the use of spermacidal creams. None of them are
very reliable and couples who are serious about contraception should not use them.
Other methods include the SAVE PERIOD and Spermacidal creams.
SAVE PERIOD
Intercourse is avoided during the fertile period. It is normalle calculated as follows:
Sperms can survive up to seven days and the ovum (egg cell) up to 3 days. Than from the length of
cylce the expected date of ovulation is calculated. intercourse is than avoided during the seven days before
( some people add two more days ) and the three days after ( 2 days also added somtimes). We are sexual and
emotional beiings and many couples will expierence diificulty in keeping to the save periods.
Spermacidals
The sperm killing creams are very unreliable on their own and should only be used with male and female
condoms and the diaphram.
The withdrawal method ( the male partner withdraws before ejaculation) is completely unreliable.
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The next page will discuss abnormal and irregular menstruations. This is usually called hormonal imbalances by the general public.
Go to the top of the page.
LAST UPDATE: 02 January 2003
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Copyright FemaleHealthMadeSimple 2001